Closing the gap – detection of clinically relevant von Willebrand disease in emergency settings through an improved algorithm based on rotational Thromboelastometry
نویسندگان
چکیده
منابع مشابه
Von Willebrand Disease: An Update
Von Willebrand disease (VWD) is the common autosomal bleeding disorder caused by a quantitative and/ or qualitative defect in the Von Willebrand Factor (VWF), a large multimeric multifunctional plasma glycoprotein which plays a critical role in hemostasis. It is essential for platelet adhesion to damaged endothelium as well as platelet interactions at high shear stress. VWF has a direct role in...
متن کاملAN IMPROVED INTELLIGENT ALGORITHM BASED ON THE GROUP SEARCH ALGORITHM AND THE ARTIFICIAL FISH SWARM ALGORITHM
This article introduces two swarm intelligent algorithms, a group search optimizer (GSO) and an artificial fish swarm algorithm (AFSA). A single intelligent algorithm always has both merits in its specific formulation and deficiencies due to its inherent limitations. Therefore, we propose a mixture of these algorithms to create a new hybrid optimization algorithm known as the group search-artif...
متن کاملThe role of exon 45 and 16 in the pathogenesis of Von Willebrand disease in Iranian Patients
Abstract Background Von Willebrand disease (VWD) is an autosomal recessive congenital bleeding disorder with deficiency or dysfunction of von Willebrand factor (VWF). The gene encoding for the VWF is located on chromosome 12, which is 178 Kb with 52 exons. Various mutations of this gene is responsible for the clinical features of VWD, but some single nucleotide polymorphisms make the molecu...
متن کاملReport on von Willebrand Disease in Malaysia
BACKGROUND Von Willebrand disease (vWD) is an inherited hemostatic disorder that affects the hemostasis pathway. The worldwide prevalence of vWD is estimated to be 1% of the general population but only 0.002% in Malaysia. AIM Our present paper has been written to disclose the statistical counts on the number of vWD cases reported from 2011 to 2013. MATERIAL AND METHODS This article is based...
متن کاملscreening of von willebrand disease in iranian women with menorrhagia
conclusions the high prevalence of vwd among our patients was the same as other previous reports, suggesting low awareness about this disease and under diagnosis of mild cases. results mean age of our patients was 32.5 ± 10.6 years. the level of von willebrand factor in 22.5% and von willebrand activity in 19.6% of patients was abnormal. the prevalence of vwd among patients with menorrhagia was...
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ژورنال
عنوان ژورنال: BMC Anesthesiology
سال: 2019
ISSN: 1471-2253
DOI: 10.1186/s12871-018-0672-8